Level of insulin-like growth fa ctor in greco-roman wrestlers Anna Kasperska, Piotr Żurek, Agnieszka Zembroń-Łacny Journal of Combat Sports and Martial Arts 2011; 2(1):19-22 ICID: 1047115
Article type: Original article
IC™ Value: 5.32
Abstract provided by Publisher
Introduction. IGF-I plays an important role in muscle regeneration and hypertrophy due to the ability to stimulate the activation, proliferation and differentiation of muscle satellite cells. The study was designed to estimate the level of insulin-like growth factor in wrestler during preparatory and competition training periods and its relation to muscle damage. Material and methods. Six high-qualified wrestlers, members of national team, were observed during two training periods differed in type and intensity exercise. In serum, concentrations of insulin-like growth factor (IGF-I) was measured. Total creatine kinase (CK) activity was determined as a marker of muscle damage. Results. Wrestlers demonstrated higher level of muscle damage at 24 h after the hard training session. Serum CK activity reached the higher values during competition than preparatory period. IGF-I concentration tended to high values in preparatory period. Analysis of percent changes in CK revealed that increase in muscle damage stimulates increase IGF-I concentration. IGFI did not correlate with body composition. Conclusions. The study has demonstrated that wrestling training period has not significantly influence on insulin-like growth factor I. However, the release of IGF-I to blood may be related to extent of skeletal muscle damage.